Author: Case Adams, Naturopath - greenmedinfo

Honey, and combinations of honey and herbs have been used for thousands of years to counteract various ailments including infections. And honey and ginger has been used as a healing combination for many conditions. But few realized just how antibiotic honey was - until recently.

Researchers from Ethiopa's College of Medicine at the University of Gondar have determined that a combination of honey and ginger extract powder will inhibit the growth of superbugs such as MRSA (methicillin-resistant Staphylococcus aureus), Escherichia coli and Klebsiella pneumoniae - some of the most lethal 'superbugs' known.

The researchers conducted a laboratory study to test the inhibition ranges – using a standardized approach of measuring mean inhibition after culturing the bacteria in a broth solution and then using agar as a medium for measurement. The broths were cultured with the antibiotics for 20-24 hours to measure their effect upon the bacteria.

The researchers separately tested Ethiopian honey, ginger powder and a combination of the two against three different antibiotics. The researchers also tested a water extract of the ginger.

The antibiotics tested were methicillin, amoxicillin and penicillin – three of the most successful antibiotics in our pharmaceutical arsenal.

The researchers conducted five tests for each treatment. These included the following bacteria:

Staphylococcus aureus (MRSA and non-MRSA)
Escherichia coli (two different strains)
Klebsiella pneumoniae

The research determined that both the honey and the ginger extract powder (alcohol extract) independently had greater inhibition levels than any of the antibiotics. The only antibiotic to come close to the inhibition of either of these was amoxicillin – which was close to the ginger extract. And this was only on the non-MRSA S. aureus. The ginger and the honey – each alone – beat out all three of these antibiotics in terms of mean inhibition levels.

The numbers tell it all. Honey and ginger extacts each had an average mean inhibition of 19.23 among all five bacteria – ranging from 13 to 24.

Meanwhile the methicillin had an average mean inhibition of 4.00 (ranging from 0 to 13), amoxicillin had an average inhibition of 12.25 (ranging from 7 to 22) and penicillin had an average inhibition of 13.25 (ranging from 9 to 20).

And the combination of the ginger extract and the honey had even greater antibiotic properties, with mean inhibition levels averaging 25.62 and ranging from 19 to 30 – beating out all the pharmaceutical antibiotics by a landslide.

How was the ginger extract made?

The ginger extract powder was made by slicing ginger root and drying at 37°C for 24 hours. These dried ginger pieces were then ground and blended with methanol and ethanol. A 50% solution of ginger was the result.

The ginger extract powder was then blended with 100% honey at a one-to-one (50/50) basis.

The water extract of the ginger had no inhibition of the bacteria. This what other research has indicated – that alcohol apparently extracts the antibiotic constituents from the ginger.

The implications of this research are vast. Both honey and ginger repel dangerous superbugs more than our most lethal antibiotics. These 'superbugs' have specifically armed themselves to counteract these overused antibiotics.

What about honey and ginger? Couldn't these 'superbugs' eventually figure out how to counteract those treatments as well?

Nature works with completely different mechanisms than static antibiotics. How is that?

It is a fact that bacteria are always present around bee hives. Bacteria are also constantly present around the roots of a ginger plant – in the soil.

In fact, soils maintain some of the highest levels of bacteria.

So how did the honey and the ginger survive the bacteria onslaught before being harvested?

Living organisms are in constant motion. They are not static. Ginger plants, for example, are constantly producing their own antibiotic mechanisms to repel bacteria. These include producing acids that break down bacteria on contact. They also include using soil-based organisms to territorialize and inhibit bacteria invasion.

These antibacterial measures that plants utilize are incorporated into the flowers where pollen is produced. This pollen is collected by bees and brought to the hive.

The bees also employ their own antibacterial measures to prevent infection in the hive. These include employing their own probiotic bacteria colonies and producing their own antibiotics which are secreted from their saliva.

Propolis, in fact, is the product produced from the bee's saliva and various plant resins. It has been shown to be significantly antibiotic.

So why do these antibiotic strategies beat out antibiotics like methicillin, amoxicillin and penicillin? Because these pharma antibiotics are static. They work the same way every time.

This means that bacteria like MRSA staph and E. coli can figure out a workaround. They can figure out how those antibiotics work and just develop measures that counteract them. Then they pass on that workaround to other bacteria in the form of plasmids.

Why? Because bacteria are alive, and they want to survive.

But so do bees, and so do plants, and so do other organisms these utilize. And this creates a moving target.

We might compare it to two opposing nations. When one country produces a certain weapon, the other nation will produce another one to counteract it. Then they will produce a new one, which the first nation will develop a means to counteract it.

This mutual counteractivity produces something biologists call evolution. In each species' quest to survive, their defense mechanisms evolve.

It is for this reason that using nature to help us counteract infection is far more sustainable than creating temporary, environment-polluting pharmaceuticals that only create resistant 'superbugs' in the end.

Yalemwork Ewnetu, Wossenseged Lemma, and Nega Birhane, "Synergetic Antimicrobial Effects of Mixtures of Ethiopian Honeys and Ginger Powder Extracts on Standard and Resistant Clinical Bacteria Isolates," Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 562804, 8 pages, 2014. doi:10.1155/2014/562804

Australian researchers have been astonished to discover a cure-all right under their noses — a honey sold in health food shops as a natural medicine. Far from being an obscure health food with dubious healing qualities, new research has shown the honey kills every type of bacteria scientists have thrown at it, including the antibiotic-resistant “superbugs” plaguing hospitals and killing patients around the world. Some bacteria have become resistant to every commonly prescribed antibacterial drug.

But scientists found that Manuka honey, as it is known in New Zealand, or jelly bush honey, as it is known in Australia, killed every bacteria or pathogen it was tested on. It is applied externally and acts on skin infections, bites and cuts. The honey is distinctive in that it comes only from bees feeding off tea trees native to Australia and New Zealand, said Dee Carter, from the University of Sydney’s School of Molecular and Microbial Biosciences. The findings are likely to have a major impact on modern medicine and could lead to a range of honey-based products to replace antibiotic and antiseptic creams.

Professor Carter’s two sons, Marty, 8 and Nicky, 6, think it’s funny the way their mother puts honey on their sores. But she swears by it, telling stories of how quickly it cures any infection. “Honey sounds very homey and unscientific, which is why we needed the science to validate the claims made for it,” she said.

The curative properties of various types of honey have been known to indigenous cultures for thousands of years, and dressing wounds with honey was common before the advent of antibiotics. “Most bacteria that cause infections in hospitals are resistant to at least one antibiotic, and there is an urgent need for new ways to treat and control surface infections,” Professor Carter said. “New antibiotics tend to have short shelf lives, as the bacteria they attack quickly become resistant.

Many large pharmaceutical companies have abandoned antibiotic production because of the difficulty of recovering costs. Developing effective alternatives could therefore save many lives.” Professor Carter said the fascinating thing was that none of the bacteria researchers used to test the honey, including superbugs such as flesh-eating bacteria, built up any immunity. She said a compound in the honey called methylglyoxal — toxic on its own — combined in unknown ways with other unidentified compounds in the honey to cause “multi-system failure” in the bacteria.

The results of the research project are published in this month’s European Journal of Clinical Microbiology and Infectious Diseases.


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Honey and Ginger Beat Antibiotics in Inhibiting Superbugs